macpymol (DeLano Scientific LLC PyMOL)
90
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DeLano Scientific LLC PyMOL
macpymol
Macpymol, supplied by DeLano Scientific LLC PyMOL, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/macpymol/macpymol/pm39481007-446-5-5
Average 90 stars, based on 1 article reviews
Macpymol, supplied by DeLano Scientific LLC PyMOL, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/macpymol/macpymol/pm39481007-446-5-5
Average 90 stars, based on 1 article reviews
macpymol - by Bioz Stars,
2026-09
90/100 stars
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other:Article Title: Functional analysis of novel splicing and missense mutations identified in the ASS1 gene in classical citrullinemia patients. Article Snippet: 22 Article history: 23 24 25 26 27 28 29 30 31 32 T E D P Received 3 May 2014 Received in revised form 16 August 2014 Accepted 23 August 2014 Available online xxxx Generated:Article Title: Antibody 27F3 broadly targets influenza A group 1 and group 2 hemagglutinins through a further variation in V H 1-69 antibody orientation on the HA stem Article Snippet: .. Structure figures were generated by Article Title: Functional Analyses of the Three Simian Hemorrhagic Fever Virus Nonstructural Protein 1 Papain-Like Proteases Article Snippet: .. Homology models were generated using MODELLER ( 25 ) ( http://salilab.org/modeller/ ) as implemented in the Max Planck Institute's Bioinformatics Toolkit ( http://toolkit.tuebingen.mpg.de/ ), and the structures were rendered and compared using Article Title: Comprehensively Characterizing the Thioredoxin Interactome In Vivo Highlights the Central Role Played by This Ubiquitous Oxidoreductase in Redox Control Article Snippet: .. The figure was generated using Selection:Article Title: The Evolution of the Mammalian ABCA6 -like Genes: Analysis of Phylogenetic, Expression, and Population Genetic Data Reveals Complex Evolutionary Histories Article Snippet: .. Amino acid sites identified as under positive selection in the ungapped alignments were matched to positionally homologous sites in the cryo-EM structure of human ABCA1 (PDB ID: 5XJY) via a multiple sequence alignment using MUSCLE ( ) and subsequently visualized in Sequencing:Article Title: The Evolution of the Mammalian ABCA6 -like Genes: Analysis of Phylogenetic, Expression, and Population Genetic Data Reveals Complex Evolutionary Histories Article Snippet: .. Amino acid sites identified as under positive selection in the ungapped alignments were matched to positionally homologous sites in the cryo-EM structure of human ABCA1 (PDB ID: 5XJY) via a multiple sequence alignment using MUSCLE ( ) and subsequently visualized in Mutagenesis:Article Title: Three novel mutations of ARG1 identified in Chinese patients with argininemia detected by newborn screening. Article Snippet: Three novel mutations of ARG1 identified in Chinese patients with argininemia detected by newborn screening |
![Type IB DNA topoisomerase. a) Human TOP1B (TOPO70) crystal structure with DNA and topotecan (TPT). Surface representation of the N-terminally truncated TOPO70 (lacking the first 174 residues) in orange with DNA (sticks) and TPT (blue balls), PDB# 1K4T [100]. All structure figures were generated using MacPyMol <t>0.99rc6</t> (DeLano Scientific, San Carlos, CA). b) Schematic representation of eukaryotic DNA topoisomerase I (TOP1B) catalytic cycle where the covalent enzyme-DNA intermediate constitutes the sole cellular target of camptothecin (CPT). Topotecan and irinotecan as FDA approved CPT analogs. TOP1B non-covalently circumscribes duplex DNA. The active side tyrosine cleaves one strand forming a 3’phospho-tyrosyl bond, which covalently links the enzyme to the 3’end of DNA. After DNA relaxation by a controlled rotation mechanism, the DNA ends religate and TOP1B may dissociate from the DNA. CPT intercalates into the cleavage site preventing religation of the DNA ends. The reversible drug-stabilized enzyme-DNA complex can be converted into lethal DNA lesions in collisions with processive replication or transcription machinery. See text for more details](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_4606/pmc09254606/pmc09254606__nihms-878366-f0002.jpg)